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Case | Age | Sex | Location | Presentation | Treatment | Follow-up |
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Crighton and Botha [15] | 58 | F | GEJ | Progressive dysphagia due to IPMN | Laparoscopic/thorascopic ILE | Asymptomatic at 3 months |
Temes et al. [10] | 24 | F | 4.5 cm mass 3 cm proximal to the GEJ | 5 days of nausea, vomiting, fever, chest pain, SOB due to esophageal rupture, and empyema | Esophageal enucleation, esophageal mucosa, and muscle closed | Asymptomatic at 1 year |
Lowry et al. [1] | 25 | M | Mass located in submucosa of distal esophagus | RUQ and epigastric abdominal pain. EGD showed fistulous tracts 3 cm proximal to GEJ and stomach nodule | VATS resection | Asymptomatic at 2 months |
Noffsinger et al. [5] | 47 | F | Distal esophagus | Epigastric abdominal pain, unable to tolerate solid foods, poor appetite, and weight loss for 2 weeks that was found to have 9 cm mass at the GEJ | ILE, pyloroplasty, Witzel jejunostomy | Infections and respiratory distress postoperative |
Goto et al. [13] | 63 | M | ∼2 cm in diameter submucosal tumor in the middle third of esophagus | Asymptomatic, incidental finding | Conservative management | Asymptomatic for 5 years |
Ulrych et al. [17] | 34 | M | Tumor arising from the lower esophagus | Several years of dyspepsia with 3 months of progressive dysphagia, odynophagia, and regurgitation. Weight loss and weakness. | Left posterolateral thoracotomy, primary anastomosis, and partial fundoplication | Asymptomatic at 3 months |
Gananadha and Hunt [12] | 26 | F | Mass located in the wall of the distal esophagus; caudal portion was involved with GEJ | Episodes of severe epigastric pain, occurring after food intake, and nausea | Diagnostic laparoscopy discovered mass in the wall of distal esophagus. Cephalad portion was cystic which was separated from esophageal mucosa. Caudal portion was excised using endo-GIA stapler. Partial Dor fundoplication performed afterwards. | Asymptomatic at 2 months |
Roshe et al. [9] | 45 | M | Distal esophagus | Dysphagia for 6 weeks | Left thoracoabdominal esophagogastrectomy | Asymptomatic |
Razi [7] | 43 | M | Distal esophagus | Massive upper GI bleeding | Thoracotomy for removal of the pleural over the esophagus; tumor was enucleated from the esophageal wall | Asymptomatic |
Salo et al. [6] | 25 | M | Distal esophagus | Nonspecific upper abdominal discomfort, heartburn, and vomiting for 1 year preoperatively. 3 years postoperatively, EGD showed reflux esophagitis. | Intramural esophageal cyst was enucleated by right thoracotomy. Reflux was treated with metoclopramide and ranitidine. | N/A |
Shalaby et al. [16] | 52 | M | Mass located at GEJ | Episodic dysphagia | Small food boluses | Asymptomatic |
Guillou et al. [8] | 60 | M | Ulcerated mass located at GEJ | Epigastric pain, dysphagia, and weight loss. | Tumor resection by left thoracotomy with proximal stomach resection; esophagogastric anastomosis | Asymptomatic at first but then developed bronchopneumonia and died 3 months postoperatively |
Rodriguez et al. [11] | 41 | F | Submucosal mass found at GEJ extending into lesser curvature of stomach | Dysphagia and epigastric pain | Total gastrectomy with Roux-en-Y esophagojejunostomy | N/A |
Garn et al. [14] | 38 | F | Submucosal tumor of GEJ | GERD | Endoscopically assisted laparoscopic resection | Asymptomatic |
Salim et al. [18] | 29 | M | Irregularity of Z-line in distal esophagus | Epigastric pain radiating to the chest, worsened by hunger. Dysphagia to solids. | N/A | N/A |
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