Case Report

Endoscopic Drainage of Giant Pancreatic Pseudocysts Using Both Lumen-Apposing Metal Stent and Plastic Stent: A Report of Two Cases and Review of the Current Literature

Table 2

Characteristics of the 24 most reported giant pancreatic pseudocysts.

VariableValue

AgeMean: 50.4 years, range: 16–81
Male : female ratio1 : 0.5
Cause
 Acute pancreatitis18/23 (78%)
 Chronic pancreatitis4/23 (17.4%)
 Trauma1/23 (4.3%)
Clinical presentation
 Time of pseudocyst presentation after acute pancreatitisMean: 7 weeks, range: 3–20 weeks
 Abdominal pain20/22 (91%)
 Abdominal distention7/22 (32%)
 Abdominal mass5/22 (22.7%)
 Anorexia4/22 (18%)
 Early satiety4/22 (18%)
 Weight loss3/22 (13.6%)
 Vomiting2/22 (9%)
 Fever2/22 (9%)
Laboratory investigations
 Elevated WBC4/15 (26%)
 Elevated amylase or lipase16/16 (100%)
 Normal CEA and CA19-98/8 (100%)
Diagnosis
 Abdominal CT scan22/24 (92%)
 Abdominal US1/24 (4%)
 Diagnostic laparoscopy1/24 (4%)
 Cyst size on CT or US (largest dimension)Mean: 16.7 cm (10–35 cm)
Management
(1) EUS-guided drainage (14 cases)
Time for stent removal after EUSMean: 5.8 weeks, range: 2–9 weeks
Types of stents used
 Metallic4/13
 Plastic (double pigtail)5/13
 Both4/13
Complications
 Recurrence of the pseudocyst5/14 need second drainage (35%), and only 1 case needs third drainage (7%)
 Pseudocyst infection1/14 (7%)
 Stent migration2/14 (14%)
 Necrosectomy needed3/14 (21%)
Time of dischargeMean: 2.6 days
(2) Open surgery or laparoscopic (9 cases)
Time of dischargeMean: 10 days

CEA: carcinoembryonic antigen; EUS: endoscopic ultrasound.