Case Report
Allografting for Bosutinib, Imatinib, Nilotinib, Dasatinib, and Interferon Resistant Chronic Myeloid Leukemia without ABL Kinase Mutation
Table 1
A brief summary of the CML treatment schedule including the drug, dosage, duration, and response/event.
| Drug | Dose | Duration | Response/event |
| Bosutinib | 400 mg/day | 14 months | Complete cytogenetic response | Imatinib Mesylate | 400 mg/day | 2 months | Hematologic adverse event (pancytopenia) | Nilotinib | 2 × 400 mg/day | 4 months | Molecular relapse | Dasatinib | 100 mg/day | 3 months | No molecular response, minor cytogenetic response | Dasatinib + IFN 2a | 140 mg/day + 3 MU/day | 3 months | Blastic crisis (BP) | Dasatinib | 100 mg/day | 1 month | Leukemic transformation |
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