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Case Reports in Hematology
Volume 2012, Article ID 167653, 4 pages
Case Report

Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature

Department of Diagnostic Haematology, The Royal Melbourne Hospital, Parkville, VIC 3050, Australia

Received 29 December 2011; Accepted 1 February 2012

Academic Editors: E. Arellano-Rodrigo and R. Tiu

Copyright © 2012 Michael Gilbertson et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We present the case of a 70-year-old woman who had a bone marrow examination performed to investigate marked thrombocytopenia in the context of a recent history of metastatic glucagonoma. Surprisingly this identified marked dysmegakaryopoiesis and fulfilled diagnostic criteria for refractory cytopenia with multilineage dysplasia, with a relatively uncommon associated cytogenetic lesion t(1;7). We present the case and review the literature of this cytogenetic lesion.