Successful Control of Disseminated Intravascular Coagulation by Recombinant Thrombomodulin during Arsenic Trioxide Treatment in Relapsed Patient with Acute Promyelocytic Leukemia

Figure 1

Clinical course of disseminated intravascular coagulation (DIC). The patient was admitted on day 1. The administration of recombinant thrombomodulin (rTM) was started on day 4, and then the administration of arsenic trioxide (ATO) was started on day 5. Fibrin/fibrinogen degradation product (FDP) levels decreased immediately, and fibrinogen levels gradually increased, indicating DIC was improved.