More Common Than You Think: Common Variable Immune Deficiency

Table 1

Clinical manifestations of Q fever [1–6].

Symptoms	Karagiannis et al., 2009 [1]	Sampere et al., 2003 [2]	Raoult et al., 2000 [3]	Domingo et al., 1999 [4]	Tselentis et al., 1995 [5]	Tissot Dupontet al., 1992 [6]	Average (𝑛=2,000)
	𝑛=73	𝑛=66	𝑛=1383	𝑛=63	𝑛=98	𝑛=323
Fever	25%	84%	91%	100%	92%	82%	87%
Hepatitis		33%	62%	48%	52%		60%
Malaise	39%	33%	62%	48%	52%	53%	58%
Headache	41%	42%	51%	56%			50%
Chills		29%		59%			44%
Pulmonary involvement	22%	56%	34%	41%	89%	38%	38%
Myalgia/arthralgia	9%	41%	37%	46%			36%
Thrombocytopenia			35%				35%
Cough	37%	27%		35%			33%
Hepatomegaly		24%		54%	22%		31%
GI symptoms		27%		19%	16%		18%
Splenomegaly				22%	11%		16%
Weight loss	11%						11%
Rash			11%	2%	2%	21%	12%
Lymphadenopathy					7%		7%
Palpitations			4%				4%
Neurological symptoms			1%		12%	9%	3%
Jaundice	2%						2%
Myocarditis			1%				1%
Pericarditis			1%				1%