A Unique “Composite” PTLD with Diffuse Large B-Cell and T/Anaplastic Large Cell Lymphoma Components Occurring 17 Years after Transplant

<table>Conventional cytogenetics and FISH analysis of the lymphoma. (a) Representative karyotype showing complex numerical and structural abnormalities. (b) and (c) FISH analysis using LSI ABL (9q34, red) and LSI BCR (22q11.2, green) dual color probes shows approximately 3–8 signals for chromosome 9 (red) and chromosome 22 (green) in anaplastic large cell lymphoma-like area. (d) FISH analysis using the same probes shows approximately 4 signals for chromosome 9 (red) and chromosome 22 (green) in conventional diffuse large B-cell lymphoma area.</table>

Case Reports in Hematology

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Figure 3: A Unique “Composite” PTLD with Diffuse Large B-Cell and T/Anaplastic Large Cell Lymphoma Components Occurring 17 Years after Transplant 