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Case Reports in Hematology
Volume 2013 (2013), Article ID 735715, 2 pages
http://dx.doi.org/10.1155/2013/735715
Case Report

Postpartum Acquired Hemophilia: A Rare Cause of Postpartum Hemorrhage

1Department of Internal Medicine, University of New Mexico-Albuquerque, 1 University of New Mexico, MSC10 555, Albuquerque, NM 87131, USA
2Department of Internal Medicine, Texas Tech University Health Sciences Center, 4800 Alberta Avenue, El Paso, TX 79905, USA
3Department of Obstetrics and Gynecology, Texas Tech University Health Sciences Center, 4800 Alberta Avenue, El Paso, TX 79905, USA

Received 12 January 2013; Accepted 5 February 2013

Academic Editors: G. Damaj, D. Galanakis, and S. Storti

Copyright © 2013 Srikanth Seethala et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A 36-year-old female started having postpartum vaginal bleeding after normal vaginal delivery. She underwent hysterectomy for persistent bleeding and was referred to our institution. An elevation of PTT and normal PT made us suspect postpartum acquired hemophilia (PAH), and it was confirmed by low factor VIII activity levels and an elevated factor VIII inhibitor. Hemostasis was achieved with recombinant factor VII concentrates and desmopressin, and factor eradication was achieved with cytoxan, methylprednisolone, and plasmapheresis.