Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Hematology
Volume 2013 (2013), Article ID 934781, 4 pages
http://dx.doi.org/10.1155/2013/934781
Case Report

Malignant Phyllodes Tumor and Acute Megakaryoblastic Leukemia Sharing a Common Clonal Origin

1Department of Hematology, University of Oslo, P.O. Box 4950, Nydalen, 0424 Oslo, Norway
2Department of Pathology, University of Oslo, P.O. Box 4950, Nydalen, 0424 Oslo, Norway
3Institute of Clinical Medicine, University of Oslo, P.O. Box 4950, Nydalen, 0424 Oslo, Norway
4Department of Nuclear Medicine, Oslo University Hospital, University of Oslo, P.O. Box 4950, Nydalen, 0424 Oslo, Norway
5Section for Cancer Cytogenetics, Institute for Medical Informatics, University of Oslo, P.O. Box 4950, Nydalen, 0424 Oslo, Norway
6Department of Oncology, University of Oslo, P.O. Box 4950, Nydalen, 0424 Oslo, Norway
7Department of Pathology, Oslo University Hospital, Radiumhospitalet, P.O. Box 4950, Nydalen, 0424 Oslo, Norway

Received 2 August 2013; Accepted 12 September 2013

Academic Editors: E. Arellano-Rodrigo, N. Hamerschlak, and S. Tauro

Copyright © 2013 Yngvar Fløisand et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. E. Duchayne, O. Fenneteau, M.-P. Pages et al., “Acute megakaryoblastic leukaemia: a national clinical and biological study of 53 adult and childhood cases by the Groupe Français d'Hématologie Cellulaire (GFHC),” Leukemia and Lymphoma, vol. 44, no. 1, pp. 49–58, 2003. View at Publisher · View at Google Scholar · View at Scopus
  2. Y. Hirai, T. Yoshimasu, S. Oura, and Y. Okamura, “Mediastinal germ cell tumor with acute myeloid leukemia and growing teratoma syndrome,” Interactive Cardiovascular and Thoracic Surgery, vol. 12, no. 1, pp. 96–97, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. H. Hiramatsu, T. Morishima, H. Nakanishi et al., “Successful treatment of a patient with Klinefelter's syndrome complicated by mediastinal germ cell tumor and AML(M7),” Bone Marrow Transplantation, vol. 41, no. 10, pp. 907–908, 2008. View at Publisher · View at Google Scholar · View at Scopus
  4. M. Ladanyi, F. Samaniego, V. E. Reuter et al., “Cytogenetic and immunohistochemical evidence for the germ cell origin of a subset of acute leukemias associated with mediastinal germ cell tumors,” Journal of the National Cancer Institute, vol. 82, no. 3, pp. 221–227, 1990. View at Google Scholar · View at Scopus
  5. A. C. Xavier, Y. Ge, and J. W. Taub, “Down syndrome and malignancies: a unique clinical relationship—a paper from the 2008 William Beaumont Hospital Symposium on Molecular Pathology,” Journal of Molecular Diagnostics, vol. 11, no. 5, pp. 371–380, 2009. View at Publisher · View at Google Scholar · View at Scopus
  6. C. R. Nichols, R. Hoffman, and L. H. Einhorn, “Hematologic malignancies associated with primary mediastinal germ-cell tumors,” Annals of Internal Medicine, vol. 102, no. 5, pp. 603–609, 1985. View at Google Scholar · View at Scopus
  7. S. H. DeMent, J. C. Eggleston, and J. L. Spivak, “Association between mediastinal germ cell tumors and hematologic malignancies. Report of two cases and review of the literature,” American Journal of Surgical Pathology, vol. 9, no. 1, pp. 23–30, 1985. View at Google Scholar · View at Scopus
  8. F. A. Tavasoli, Pathology and Genetics of Tumours of the Breast and Female Genital Organs, World Health Organization Classificiation of Tumours, IARC Press, Lyon, France, 2003.
  9. S. A. Khan and S. Badve, “Phyllodes tumors of the breast,” Current Treatment Options in Oncology, vol. 2, no. 2, pp. 139–147, 2001. View at Google Scholar · View at Scopus
  10. C. R. Nichols, B. J. Roth, N. Heerema, J. Griep, and G. Tricot, “Hematologic neoplasia associated with primary mediastinal germ-cell tumors,” The New England Journal of Medicine, vol. 322, no. 20, pp. 1425–1429, 1990. View at Google Scholar · View at Scopus