Unusual T-Lymphoblastic Blast Phase of Chronic Myelogenous Leukemia

Figure 2

Bone marrow and lymph node biopsies of Case 2. The bone marrow demonstrated typical morphology of chronic myelogenous leukemia, chronic phase ((a) H&E: 200x; (b) H&E: 400x) and FISH showed BCR/ABL1 fusion (c); lymph node demonstrated lymphoblastic lymphoma morphology ((d) H&E: 200x; (e) H&E: 400x) with a T-lymphoblastic immunophenotype by flow cytometry (not shown) and was positive for TdT ((f) immunohistochemistry: 200x).

(a)

(b)

(c)

(d)

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(f)