Open Questions in the Management of Nodular Lymphocyte Predominant Hodgkin Lymphoma

Table 1

Histological features of NLPHL and cHL [8].

	NLPHL	cHL
Malignant cells	Nodular patterns of LP cells	Diffuse, interfollicular, and nodular Reed-Sternberg cells
Background appearance	Predominantly small B-lymphocytes	Reactive cellular infiltrate
CD30	−	+
CD15	−	+
CD45	+	−
CD79a	+	−
CD20	++	−