Case Report
Idiopathic Acquired Hemophilia A with Undetectable Factor VIII Inhibitor
Table 2
The laboratory data and clinical course of acquired hemophilia A.
| | | Day 1 | Day 7 | Day 31 | Month 3 | Month 6 | Month 8 |
| | aPTT (s) | 44.2 | NA | NA | NA | NA | NA | | aPTT ratio (PAT/normal) | 1.7 | NA | NA | NA | NA | NA | | FVIII activity (%) | 16 | 6 | 44 | 136 | 220 | 166 | | FVIII inhibitor (BU/mL) | 0.0 | NA | 0.0 | NA | NA | NA | | Hemoglobin (g/dL) | 8.5 | 10.0 | 12.2 | 14.6 | 15.1 | 14.3 | | Reticulocyte count (%) | 6.4 | NA | 6.2 | 3.8 | 2.7 | 2.3 | | Absolute reticulocyte Count (103/μL) | 191.0 | NA | 209.0 | 154.0 | 117.0 | 98.2 | | Platelet (103/μL) | 267 | 322 | 180 | 201 | 150 | 209 | | Immunosuppressive |
Prednisone: 80 mg/day PO
cyclophosphamide: 100 mg/day PO | Prednisone: 60 mg/day PO
cyclophosphamide: 100 mg/day PO* | Prednisone: 30 mg/day PO | Prednisone: 10 mg/day PO | None |
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Cyclophosphamide stopped at day 38.
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