Case Report

Managing a Rivaroxaban Bleed: Understanding the Difficulties in Acute Reversal of the New Oral Anticoagulants through a Case Report

Table 1

Timeline of hospitalization.

Hospital day no.12345

Hgb (g/dL)6.8, 8.3, 7.2, 5.75.1, 9, 8.39.3, 9.7, 9.28.2, 7.8, 9.39.5

PT (seconds)14.114.612.6

aPTT (seconds)27.221.521.9

INR1.31.31.1

Intervention1,800 units of prothrombin complex concentrate, intravenous fluids, and 2 units of packed red blood cells2.5 mg conjugated estrogen and 2 units of packed red blood cellsBalloon tamponade and 2 units of packed red blood cellsEndometrial ablation and 1 unit of packed red blood cellsDischarge

Hgb: hemoglobin, PT: prothrombin time, aPTT: activated partial thromboplastin time, INR: international normalized ratio.