Transformation of Follicular Lymphoma to Double Hit B-Cell Lymphoma Causing Hypercalcemia in a 69-Year-Old Female: A Case Report and Review of the Literature
Figure 2
(a) 100x H&E image shows a monomorphic infiltrate of small round blue cells with adjacent necrosis, (b) 400x H&E high power demonstrates medium sized cells with admixed apoptotic bodies and mitotic figures reminiscent of Burkitt or a Burkitt-like lymphoma, and (c) Ki-67: high proliferation rate over 90% supports the morphologic impression and is indicative of an aggressive lymphoma.
