“Almost Bleeding to Death”: The Conundrum of Acquired Amegakaryocytic Thrombocytopenia
Figure 1
((a)-(b)) The peripheral blood shows normal mature neutrophils and lymphocytes with normal red blood cell morphology. Rare morphologically normal platelets are identified. (c) The bone marrow aspirate shows a spectrum of normal maturation in erythroid and granulocytic precursors. No abnormal cell population is identified. (d) The bone marrow core biopsy cellularity is appropriate for age. (e) The bone marrow interstitium does not show the presence of megakaryocytes. (f) Immunohistochemistry for CD61, a megakaryocytic antigen, does not show the presence of megakaryocytes on the core biopsy tissue section.
