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Case Reports in Hematology
Volume 2015 (2015), Article ID 273565, 5 pages
Case Report

Localized Relapse of Primary Plasma Cell Leukaemia in the Central Nervous System

Department of Haematology, Aarhus University Hospital, Aarhus, Denmark

Received 10 March 2015; Accepted 17 April 2015

Academic Editor: Gandhi Damaj

Copyright © 2015 Christian W. Eskelund and Niels Frost Andersen. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Primary plasma cell leukaemia (pPCL) is a rare and aggressive form of plasma cell malignancies with a very poor prognosis. Compared to other plasma cell malignancies the tendency to extramedullary spread is increased; however central nervous system (CNS) involvement is rare and only reported in few cases. We report the case of a 61-year-old man who was diagnosed with pPCL and achieved a complete remission after autologous stem cell transplantation but had a relapse in the CNS without systemic disease.