Case Report

MALT Lymphoma of the Bladder: A Case Report and Review of the Literature

Table 1

Characteristics of reported cases of primary MALT lymphoma of the bladder on PubMed as of June 2015.

AuthorAgeSexPresenting symptomTreatmentFollow-up (Months)Outcome

Hughes et al., [22]81FemaleHematuriaDiathermy TURBT12NED
Ando et al., [16]77FemaleUrinary retentionTURBT36NED
Kempton et al., [23]64FemalePartial cystectomy144Died of unknown cause
Fernandez Acenero et al., [24]73FemaleDysuria, Back painChemotherapy8Died of unknown cause
Fernandez Acenero et al., [24]50FemaleFeverChemotherapy60NED
Fernandez Acenero et al., [24]75FemaleHematuria, dysuria and Breast carcinomaChemotherapy9NED
Gallardo et al., [25]70FemaleHematuria, Dysuria, Malaise and weight lossChemotherapy24NED
Morita et al., [26]68Femalepersistent interstitial cystitisChemotherapy [Rituximab]NED
Wazait et al., [27]65FemaleHematuria, dysuria and recurrent UTI’sChemotherapy [CHOP]36NED
Hughes et al., [22]77MaleHematuriaChemotherapy [ChID]48NED
Hughes et al., [22]28MaleHematuriaChemotherapy [ChIVP]120NED
Kakuta et al., [17]84FemaleGeneral fatigue and weight lossChemotherapy [R-CHOP]
Sen et al., [28]31FemaleIncidental finding - PregnancyPostpartum Chemotherapy
Kempton et al., [23]79FemaleRadiation24Died of Myocardial infarction
Al-Maghrabi et al., [10]64FemaleHematuria, and recurrent UTIRadiation156NED
Al-Maghrabi et al., [10]69FemaleTreatment resistant UTIRadiation60NED
Al-Maghrabi et al., [10]72FemaleHematuria and recurrent UTIRadiation36NED
Al-Maghrabi et al., [10]62MaleHematuriaRadiation24NED
Tsang et al., [29]RadiationNED
Tsang et al., [29]RadiationNED
Tsang et al., [29]RadiationNED
Hughes et al., [22]76FemaleHematuriaRadiation24NED
Hughes et al., [22]66FemaleRecurrent UTIRadiationDeceased
Takahara et al., [30]85FemaleHematuriaRadiationNED
Hatano et al., [15]84FemaleHematuria and recurrent UTIRadiation12NED
Kempton et al., [23]73FemaleFulguration and Radiation120Died of unknown cause
Kempton et al., [23]27FemaleTumor resection and Radiation480Died of fibrosarcoma
Kempton et al., [23]45MaleSegmental resection and Radiation312Died of unknown cause
Kempton et al., [23]50FemaleSegmental resection and Radiation240NED
Ueno et al., [31]64FemaleIncidental findingTURBT and Radiation19Recurrence Stomach
Haddad-lacle et al., [32]54MaleLow back pain, incidental bladder massTURBT and Radiation36NED
Wazait et al., [27]70FemaleHematuriaTURBT-1 yr recurrence, Chemotherapy on recurrence60NED
Szopiński et al., [33]17FemaleIncidental findingTURBT and Chemotherapy24NED
Maninderpal et al., [34]65FemaleChronic suprapubic mass, nausea and feeling unwellTURBT and Chemotherapy3Died of Sepsis
Matsuda et al., [3]78FemaleRefractory Cystitis and renal dysfunctionTURBT and Chemotherapy [rituximab]
Kawakami et al., [35]27MaleRadiation and Chemotherapy [doxorubicin]18NED
Tasu et al., [36]75FemaleHematuriaRadiation and Chemotherapy [cyclophosphamide]36NED
Painemal et al., [37]70FemaleHematuria, Dysuria, Malaise and weight lossRadiation and Chemotherapy48NED
Hughes et al., [22]82FemaleHematuriaRadiation + Chemotherapy [ChIVP]Deceased
Terasaki et al., [19]64FemaleGeneral malaise and anemiaRadiation and Chemotherapy [Rituximab]14NED
Mizuno et al., [38]72FemaleHematuria and recurrent cystitisTURBT, Radiation and Chemotherapy [rituximab]
Bacalja et al., [39]48MaleIncidental findingTURBT, Radiation and Chemotherapy [R-CHOP]5Remission
Mayer et al., [40]70MaleBladder mass with scalp metastasisChemotherapy and Radiation for scalp and brain14Died of Brain Metastasis
van den Bosch et al., [41]59MaleHematuriatriple therapy [patient denied radiation]36NED
Fujimura et al., [42]69FemaleHematuria and anemiaAntibiotics and H. pylori therapy24NED
Terada, [43]88FemaleHematuriaAntibiotics6Markedly reduced tumor size
Lucioni et al., [20]72FemalePersistent dysuriaAntibiotics6NED
Bates et al., [11]66FemaleBladder mass12NED
Bates et al., [11]79FemaleHematuria
Bates et al., [11]59FemaleUntreated solid necrotic tumor36NED
Kröber et al., [44]57MaleObstructive dysuria
Takahashi et al., [30]71FemaleHematuria

Authors do not have access to this information.
CHOP: cyclophosphamide, hydroxydaunorubicin, vincristine, and prednisone.
R-CHOP: cyclophosphamide, hydroxydaunorubicin, vincristine, prednisone, and rituximab.
ChlVP: chlorambucil, vincristine, and prednisolone.
TURBT: transurethral resection of bladder tumors.
NED: no evidence of disease.