CD7 Positive Diffuse Large B-Cell Lymphoma Arising in a Background of Follicular Lymphoma: A Case Report and Review of the Literature

Table 1

Immunohistochemical expression of non-CD5 T-cell antigens in DLBCLs. The manuscripts noted in the table do not discriminate the various non-CD5 positive DLBCLs in germinal center versus nongerminal center phenotype. According to Suzuki et al., the rate of non-CD5 T-cell antigen expression in DLBCLs is extremely low with only ~0.3% of their known cases. Inaba et al. evaluated 10 cases of DLBCL of which 3 of them showed expression of CDC7 [6]. In another study Inaba et al. showed no cases of DLBCL with expression of CD7 by evaluation of 4 cases [7].

Number	Authors	Total patients with DLBCL	De novo/transformed	CD2	CD3	CD4	CD5	CD7	CD8	Method
1	Suzuki et al. [9]	150	De novo	1	0	0	ND	3	1	IHC
2	Inaba et al. [6]	10	De novo	1	0	0	6	3	0	FC
3	Kaleem et al. [8]	2	De novo	1	0	1	0	1	0	FC
4	Inaba et al. [7]	4	De novo	0	0	0	4	0	0	FC
5	E. Vali Betts	1	Transformed	0	0	0	0	1	0	FC and IHC

Immunohistochemistry.
Flow cytometry.
Not done.