Case Report

Uveitis and Myositis as Immune Complications in Chemorefractory NK/T-Cell Nasal-Type Lymphoma Successfully Treated with Allogeneic Stem-Cell Transplant

Table 1

Reported cases with autoimmune complications.

AuthorAgeSexLocationPrevious symptomsAutoimmune complicationsTime to diagnosisTreatmentSurvivalCause of death

Park et al. [10]40WSkinHigh fever, proximal muscle weakness, multiple skin plaques with bullae and serous dischargeDermatomyositis and hemophagocytic syndrome24 monthsCHOP → steroid, antibiotics, gamma globulin, oral cyclosporin7 daysHepatic failure, renal failure, pancytopenia, massive pleural effusion
Kim et al. [2]64MSkinPainful swelling and redness of the left upper armCellulitis or fasciitis5 monthsAntibiotics → L-asparagine chemotherapyn.r.n.r.
Chan et al. [11]68WMuscleForearm swelling and bilateral facial swellingPolymyositis4-5 weeksPrednisoloneFew daysFulminant hemophagocytic syndrome
Spadigam et al. [12]49MSkinIntermittent fever, nasal stuffiness, epistaxis and hemifacial pain, nasolabial lesionInflammatory myofibroblast3 monthsSurgery2 weeksPostoperative complications
Fei et al. [13]83WLungSkin ulceration and intermittent feverPanniculitis12 monthsAntibiotics → patient refused treatment35 daysMultiorgan failure
Chow et al. [9]27WSkinIntermittent fever, occasional night sweats, nasal congestion and hoarseness, skin nodulesPanniculitis or sarcoidosis3 monthsAntiviral/antibiotic → CHOP → ICE7 monthsSecondary hemophagocytic syndrome
Current56MSkinBilateral nasal respiratory insufficiency, anterior septal perforation, skin lesionsMyositis and uveitis13 monthsCHOP → SMILE → BMT30 monthsAlive