Case Report
Peripheral T-Cell Lymphoma of the Submandibular Salivary Gland as an Unusual Manifestation of Richter’s Syndrome: A Case Report and Literature Review
Table 1
Review of the literature for PTCL-NOS in CLL/SLL patients.
| | Authors, reference | Age/sex | Interval, CLL/SLL to PTCL-NOS (mo) | Therapy for CLL/SLL, yes (+)/no (−) | Expression of PTCL-NOS cytotoxic molecules | Discordant lymphoma | Composite lymphoma (localization) | | TIA1 | Granzyme B |
| | Martinez et al. [8] | 70/M | 156 | NA | ND | ND | + | — | | Martinez et al. [8] | 73/M | ND | NA | + | + | — | + (LN) | | Martinez et al. [8] | 59/M | 10 | + (PCT) | − | + | + | — | | Martinez et al. [8] | 73/M | 60 | + (IL-4) | + | + | + | — | | Martinez et al. [8] | 57/M | 168 | NA | + | + | + | — | | Martinez et al. [8] | 58/F | ND | NA | + | + | — | + (LN) | | Campidelli et al. [9] | 80/M | − | − | + | + | — | + (LN) | | Campidelli et al. [9] | 61/M | − | − | ND | + | — | + (BM) | | Buddula and Assad [10] | 66/M | 72 | + (PCT) | + | + | + | — | | Alomari et al. [11] | 68/F | 84 | + (PCT/RT) | − | + | — | + (LN) | | Boyer et al. [12] | 70/M | 132 | + (PCT) | ND | + | + | — |
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At PTCL-NOS diagnosis; LN: lymph node; BM: bone marrow; PCT: polychemotherapy; RT: radiotherapy; IL-4: interleukin 4; NA: not available; ND: not done; PTCL-NOS: peripheral T-cell lymphoma not otherwise specified; CLL/SLL: chronic lymphocytic leukemia/small lymphocytic lymphoma; TIA1: T-cell intracellular antigen-1.
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