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Case Reports in Hematology
Volume 2017, Article ID 3091973, 3 pages
Case Report

A Rare Case of Paraneoplastic Aortitis Associated with Chronic Myelomonocytic Leukemia

1Division of Rheumatology, Cooper University Hospital, Camden, NJ, USA
2Division of Hematology-Oncology, MD Anderson Cancer Center, Cooper University Hospital, Camden, NJ, USA

Correspondence should be addressed to Sylwia Sasinowska; ude.htlaehrepooc@aiwlys-akswonisas

Received 3 January 2017; Revised 3 April 2017; Accepted 24 April 2017; Published 25 May 2017

Academic Editor: Akimichi Ohsaka

Copyright © 2017 Sylwia Sasinowska et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Aortitis is a broad term describing inflammation of the aorta. The most common causes of aortitis are the large-vessel vasculitides giant cell arteritis and Takayasu arteritis. Other etiologies include aortitis associated with other autoimmune disorders, infectious causes, and paraneoplastic and idiopathic cases. We describe a rare case of a large-vessel arteritis occurring in association with chronic myelomonocytic leukemia (CMML). A 68-year-old female with recent diagnosis of CMML presented to our office for evaluation of abnormal chest computed tomography (CT) that showed inflammation surrounding the entirety of thoracic and abdominal aorta, consistent with aortitis. In the absence of other evident causes of large-vessel vasculitis, we attributed this finding to a paraneoplastic autoimmune phenomenon and started treatment with systemic glucocorticoids. This rare case emphasizes the need to recognize autoimmune complications in CMML and treat the inflammation along with the primary malignancy promptly.