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Case Reports in Hematology
Volume 2017, Article ID 3649397, 3 pages
Case Report

Neurological Complications following Blood Transfusions in Sickle Cell Anemia

New York Methodist Hospital, Brooklyn, NY, USA

Correspondence should be addressed to Hana Alharbi; gro.pyn@8309aah

Received 2 August 2016; Accepted 13 November 2016; Published 3 January 2017

Academic Editor: Kate Khair

Copyright © 2017 Hana Alharbi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


In Sickle Cell Anemia (SCA) patient blood transfusions are an important part of treatment for stroke and its prevention. However, blood transfusions can also lead to complications such as Reversible Posterior Leukoencephalopathy Syndrome (RPLS). This brief report highlights two cases of SCA who developed such neurological complications after a blood transfusion. RLPS should be considered as the cause of neurologic finding in patients with SCA and hypertension following a blood transfusion.