Erdheim-Chester Disease with No Skeletal Bone Involvement and Massive Weight Loss
Histologically, the hematoxylin and eosin (H&E) stain shows infiltration by histiocytes (a), 100X. The infiltrate is composed of bland-looking histiocytes with foam-cell and giant-cell forms (b), 200X. The histiocytes stain positive for CD68 immunostain (c) and negative for S100 immunostain (d).
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