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Case Reports in Hematology
Volume 2018, Article ID 2414278, 6 pages
Case Report

Breast Implant-Associated Anaplastic Large Cell Lymphoma: Case Report and Review of the Literature

1Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
2Department of Pathology, Mount Sinai Downtown, New York, NY 10003, USA
3Department of Surgery, Mount Sinai Downtown, New York, NY 10003, USA
4Department of Medicine, Mount Sinai Downtown, New York, NY 10003, USA
5Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai Hospital, New York, NY 10029, USA
6Department of Radiation Oncology, Mount Sinai Downtown, New York, NY 10003, USA

Correspondence should be addressed to Manjeet Chadha; gro.ianistnuom@ahdahc.teejnam

Received 31 August 2017; Accepted 4 December 2017; Published 21 January 2018

Academic Editor: Sotirios G. Papageorgiou

Copyright © 2018 Eva Berlin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We are reporting the case of a 58-year-old woman with history of bilateral silicone breast implants for cosmetic augmentation. At 2-year interval from receiving the breast implants, she presented with swelling of the right breast with associated chest wall mass, effusion around the implant, and axillary lymphadenopathy. Pathology confirmed breast implant-associated anaplastic large cell lymphoma (stage III, T4N2M0, using BIA-ALCL TNM staging and stage IIAE, using Ann-Arbor staging). The patient underwent bilateral capsulectomy and right partial mastectomy with excision of the right breast mass and received adjuvant CHOP chemotherapy and radiation to the right breast and regional nodes. Since completion of multimodality therapy, the patient has sustained remission on both clinical exam and PET/CT scan. We report this case and review of the literature on this rare form of lymphoma.