Case Report

Primary Myeloid Sarcoma of the Prostate: A Case Report and Literature Review

Table 1

Primary myeloid sarcoma of the prostate.

CaseAgeSymptomsHematological diagnosisTime to progression to AMLTreatmentOutcomes

1 [8]79Urinary retentionN/AN/ANoneDied shortly after TURP
2 [9]67Urinary retentionAML-M2 (FAB classification)7 monthsLymphoma-directed chemotherapy and then remission-induction chemotherapyOriginally misdiagnosed as lymphoma and received CHOP. Started remission-induction chemotherapy at AML relapse and achieved CR. Alive at 19 months after MS diagnosis
3 [10]32Dysuria, weight loss, and night sweatsAML-M5 (FAB classification)3 weeksRemission-induction chemotherapyDied 3 months after MS diagnosis
4 [11]71DysuriaAML4 monthsChemotherapy (unspecified)CR and further follow-up N/A
5 [12]71DysuriaAML-M2 (FAB classification)4 monthsRemission-induction chemotherapy and then salvage chemotherapyCR and then relapse with salvage chemotherapy with second CR; died 24 months after MS diagnosis due to brain hemorrhage
6 (present case)73Frequency and hesitancyNoneN/ARemission-induction chemotherapy followed by consolidationWithout progression to AML at 1 year after MS diagnosis

AML: acute myeloid leukemia; CHOP: cyclophosphamide; doxorubicin, vincristine, and prednisone; CR: complete remission; FAB classification: French-American-British classification; MS: myeloid sarcoma; N/A: not available; TURP: transurethral resection of the prostate.