Case Report

Two Cases of γ-Heavy Chain Disease and a Review of the Literature

Figure 1

Serum electrophoresis and immunofixation. (a) Case 1: immunofixation shows staining in the gamma region, without a corresponding stain in the light chain region. Two bands are detected in the gamma region, a major and a second minor band. (b) Case 2: immunofixation shows a broad stain in the alpha-beta region, without a corresponding region in the light chain. Immunofixation further identifies an IgMkappa paraprotein. ELP = protein electrophoresis; G: immunofixation with anti-gamma chain; identifying gamma heavy chain; A: anti-alpha chain immunofixation; M: anti-mu chain immunofixation; K: anti-kappa chain immunofixation; L: anti-lambda chain immunofixation.
(a)
(b)