Amebic Encephalitis in a Patient with Chronic Lymphocytic Leukemia on Ibrutinib Therapy

Figure 2

Microphotographs of autopsy brain sections. Hematoxylin and eosin stain. (a) A low-power view shows areas of parenchymal hemorrhage and necrosis with mixed inflammation, ×10 objective. (b) A higher power view demonstrates amebic trophozoites and occasional cysts, ×20 objective. (c) At high power, numerous amebic trophozoites can be seen intermixed with inflammatory cells and occasional multinucleated giant cells (yellow arrow), ×40 objective. (d) The amebae (black arrow) are prominent around vessels (V), ×40 objective.

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