Drug-Induced Thrombotic Microangiopathy due to Cumulative Toxicity of Ixazomib

Table 1

Common anticancer chemotherapeutic agents causing drug-induced thrombotic microangiopathy via immune-mediated mechanism or dose-dependent toxicity or both [4, 7].

Cancer therapeutic agent	Immune-mediated mechanism	Dose-dependent toxicity
Bevacizumab	—	X
Bortezomib	X	—
Carfilzomib	X	—
Ixazomib	X	—
Gemcitabine	X	X
Mitomycin	—	X
Oxaliplatin	X	—
Pentostatin	—	X
Sunitinib	—	X
Imatinib	X	—
Docetaxel	—	X