Chronic Lymphocytic Leukemia and Myelofibrosis

Table 2

Molecular characteristics of reported patients with CLL and PMF.

Report	Karyotype at CLL diagnosis	IGHV mutation, n (%)	JAK-2 mutation, n (%)	Karyotype at myelofibrosis diagnosis
Lennard et al. [6]	Not available	Not available	Not available	Not available
Nieto et al. [7]	Not available	Not available	Not available	Not available
Palta et al. [8]	Not available	Not available	Negative	Not available
Burgstaller et al. [9]	Normal	Not available	Negative	Normal
Laurenti et al. [10]	Not available	1 (25)	2 (50)	Not available
Salama et al. [14]	Not available	Negative	Negative	Not available
Todisco et al. [15]	Normal (50%)	4 (50)	3 (37.5)	Del 7 (12.5)
	t (3; 12) (12.5%)			Del 8q21, del 20q11 (12.5)
	Del 20q11 (12.5%)			Del 5q, del 13q (12.5)
	Del 5q, del 13q (12.5%)			t (3; 12) (12.5)
	Not available (12.5%)
Marchetti et al. [16]	Not available	Not available	15 (65.2)	Not available