Case Reports in Hematology / 2018 / Article / Fig 1

Case Report

Protracted Clonal Trajectory of a JAK2 V617F-Positive Myeloproliferative Neoplasm Developing during Long-Term Remission from Acute Myeloid Leukemia

Figure 1

Bone marrow biopsy (a) at diagnosis of acute myeloid leukemia (AML) demonstrating infiltration by myeloblasts; (b) after one course of AML therapy showing atypical megakaryocyte morphology and focal clustering; (c) at diagnosis of myeloproliferative neoplasm (MPN) with myeloid hypercellularity and increased megakaryocytes; and (d) at diagnosis of MPN demonstrating increased reticulin deposition.
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