Case Report
A Rare Case of Triple-Negative Essential Thrombocythemia in a Young Postsplenectomy Patient: A Diagnostic Challenge
Table 1
Trend of patient’s complete blood count (CBC) over the hospital stay with respect to timing of admission.
| | | Plt (109/L) | WBC (103/μL) | RBC (106/μL) | Hgb (g/dL) | Hct (%) |
| | Splenectomy (2 months prior to admission) | 140 | 24.2 | 2.73 | 7.8 | 22.8 | | Splanchnic venous thrombosis (admission) | 2239 | 24.6 | 3.95 | 10.4 | 33.4 | | Beginning of plateletpheresis session (day 2) | 2079 | 21.6 | 3.96 | 10.3 | 33.2 | | End of plateletpheresis session (day 2) | 402 | 16.4 | 4.32 | 11.1 | 36 | | Started hydroxyurea 1000 mg PO daily (day 4) | 670 | 13.8 | 3.17 | 8.5 | 26.2 | | Increased dose of hydroxyurea 1500 mg PO daily (day 8) | 1307 | 11.5 | 3.31 | 9 | 27.7 | | Started anagrelide 0.5 mg PO BID (day 10) | 1595 | 14.4 | 3.63 | 9.9 | 30.9 | | Discharged home (day 19) | 644 | 11.2 | 3.63 | 10.1 | 31.2 | | Anagrelide 0.5 mg PO BID discontinued (day 75) | 397 | 8.5 | 3.1 | 11.3 | 33.9 | | Decreased hydroxyurea 1000 mg PO daily (6 months) | 512 | 8.8 | 3.12 | 12.5 | 36.8 |
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