Case Reports in Hematology / 2018 / Article / Fig 1

Case Report

A Rare Case of Systemic AL Amyloidosis with Muscle Involvement: A Misleading Diagnosis

Figure 1

Muscle biopsy general features and the presence of amyloid substance. (a) Hematoxylin and eosin staining: the muscle cells show regular morphological characteristics with the exception of one hypercontracted cell; (b) Gomori staining: normal histological picture; (c) succinate dehydrogenase staining (SDH): the staining shows mild changes in myofibrillar texture; (d) ATPase pH 9.4: normal muscle fiber typing and distribution. Congo red staining without (e) or with polarized light (f): presence of amyloid around/inside the wall of perimysial vessels (×20); (g) Thioflavin S staining with fluorescence microscope: amyloid substance appears bright green in dark field. It completely includes the vessel wall of some perimysial arterioles (×20).
(a)
(b)
(c)
(d)
(e)
(f)
(g)

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.