Prolonged Myelosuppression due to Progressive Bone Marrow Fibrosis in a Patient with Acute Promyelocytic Leukemia

Figure 4

Serial bone marrow biopsies (hematoxylin-eosin (HE) and silver staining (Ag)). Only mild reticulin fibrosis was observed at the time of diagnosis. Fibrosis progressed as treatment progressed, and collagenous fibrosis was recognized. Magnification, 40x.