Case of a CD3 Negative Hepatosplenic T-Cell Lymphoma: Diagnostic and Therapeutic Challenges

Figure 5

Patient underwent open splenectomy. Pathology reported a hepatosplenic T-cell lymphoma diffusedly involving a markedly enlarged spleen, 4025 grams, 29.5 × 22.0 × 10.9 cm. The capsule is tan, remarkable for adhesions and multiple defects ranging in size from 3.7 × 1.0 cm to 16.5 × 11.5 cm. The specimen is remarkable for three possible hilar nodes ranging in size from 1.2 × 0.7 × 0.5 cm to 4.5 × 2.1 × 2.0 cm. Sectioning through the spleen reveals gray-white to yellow hemorrhagic lobular cut surfaces. No definitive grossly unremarkable splenic parenchyma can be identified.