A Case of Aggressive Multiple Myeloma with Extramedullary Involvement of the Female Reproductive System, Thyroid and Breasts
Table 1
Treatment regimens that can be used in multiple myeloma with extramedullary disease.
Stem cell transplantation eligible patients
Triplet induction therapy followed by ASCT, triplet consolidation therapy, and maintenance with lenalidomide at least
Elderly patients not eligible for stem cell transplantation
Bortezomib-melphalan-prednisone (VMP) or continuous lenalidomide-dexamethasone (Len-Dex)
Very aggressive disease especially with multiple plasmacytomas
VDT-PACE (bortezomib, dexamethasone, thalidomide, cisplatin, doxorubicin, cyclophosphamide, and etoposide) followed by ASCT if eligible and maintenance with bortezomib-based regimen
Treatment modalities under study which may be used with traditional regimens