Ibrutinib-Associated Cardiac Tamponade with Concurrent Antiplatelet Therapy

Figure 2

The effects of ibrutinib on platelet function. Btk, Bruton’s tyrosine kinase; Tec, tyrosine kinase expressed in hepatocellular carcinoma; aspirin effects thromboxane A2 receptor (TP); clopidogrel effects adenosine diphosphate (ADP) via p2y12 & p2y1 receptors; von Willebrand factor (VWF) effects glycoprotein Ib (GpIb); collagen binds glycoprotein VI (GpVI); fibrinogen binds integrin αIIbβ3. This work, “The effects of ibrutinib on platelet function,” is a derivative of “The effects of ibrutinib on platelets” by Shatzel et al., retrieved from https://onlinelibrary.wiley.com/doi/full/10.1111/jth.13651. Used under Creative Commons Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0) Generic license https://creativecommons.org/licenses/by-nc/3.0/.