Use of KRD-PACE as Salvage Therapy in Aggressive, Relapsed/Bortezomib-Refractory Extramedullary Multiple Myeloma: A Report of Two Cases and Literature Review

Table 2

KRD-PACE dosing schedule for patient 1 and KRD-PACE dosing schedule for patient 2.

28d cycle	K	R	D	P	A	C	E
A: Patient 1, KRD-PACE schedule
Dose	20 mg/m^2 (day 1) then 56 mg/m^2 thereafter	25 mg	40 mg	10 mg/m^2	10 mg/m^2	400 mg/m^2	40 mg/m^2
Schedule	Days 1, 2, 8, 9, 15, 16	Days 1–21	Days 1–4	Days 1–4	Days 1–4	Days 1–4	Days 1–4
B: Patient 2, KRD-PACE schedule
Dose	20 mg/m^2 (day 1) then 27 mg/m^2	15 mg	40 mg	10 mg/m^2	10 mg/m^2	400 mg/m^2	40 mg/m^2
Schedule	Days 1,2	Days 1–21	Days 1–4	Days 1–4	Days 1–4	Days 1–4	Days 1–4