Case Report

Recurrent Gastrointestinal Hemorrhage in Children with Philadelphia-Positive B-Cell Acute Lymphoblastic Leukemia Treated with Dasatinib: Case Reports

Table 2

Results of MRD, FISH, and qRT-PCR analyses for the patients.

Time pointLaboratory findingsPatient 1Patient 2Patient 3

TP1MRD<10−40.38%1.38%
FISHNegativeNegativeNegative
IS BCR-ABL10.0120.0150.0015
TP2MRD<10−4<10−4<10−4
FISHNegativeNegativeNegative
IS BCR-ABL1NegativeNegativeNegative
Every 6 months after chemotherapyFISHNegativeNegativeNegative
IS BCR-ABL1NegativeNegativeNegative
ABL1 mutationNegativeNegativeNegative

TP: time point; MRD: minimal residual disease; FISH: fluorescence in situ hybridization.