The Occurrence of Richter’s Syndrome during Treatment with Obinutuzumab and Chlorambucil

Figure 2

Sheets of large lymphocytes with centroblastic morphology ((a) haematoxylin and eosin stain), with positive immunohistochemistry for high Ki-67 index of 70%, CD20, and MUM1 (b)–(d), respectively.

(a)

(b)

(c)

(d)