Case Report
Intrasinusoidal Hodgkin Lymphoma; A Mimic of Anaplastic Large Cell Lymphoma
Table 1
Immunophenotypic and genetic studies.
| Anaplastic large cell lymphoma | Classic Hodgkin lymphoma |
| Immunophenotype | | T/null | T-cell (rare 5%) | CD15−/+ (0–20%) | CD15+ (75%) | PAX5 − | PAX5 weakly + (90%) | CD45 usually + | CD45 usually − | EMA + (60–100%) | EMA – (rarely + 0–5%) | CD43 + | CD43 usually − | IFR/MUM − | IFR/MUM + | ALK 1 may be + in some cases | ALK 1 − | EBER + (5–20%) | EBER + (15–75%) |
| Genetic studies | | T-cell receptor gene rearranged | | t(2,5)-NPM/ALK rearrangement | |
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