A Rare Case of Midostaurin-Associated Sweet’s Syndrome
Table 2
Diagnostic criteria for Sweet’s syndrome.
Major criteria
Minor criteria
Abrupt onset of painful erythematous papules, nodules, or plaques
Fever >38°C
Histopathological findings of dense neutrophilic infiltrates without evidence of leukocytoclastic vasculitis
Association with hematologic or visceral malignancy, inflammatory disease, or pregnancy, or preceded by upper respiratory tract infection, gastrointestinal infection, or vaccination
Dramatic response to treatment with systemic steroids or potassium iodide
Abnormalities in laboratory tests (three of four): erythrocyte sedimentation rate >20 mm/h; high C-reactive protein; leukocytes >8000, with >70% neutrophils