Case Report

Primary Pleomorphic Liposarcoma of Liver: A Case Report and Review of the Literature

Table 1


SlTumorAbberationGenes involved

(1)Myxoid/round cell liposarcoma,t(12;16)(q13;p11)TLS-CHOP
(2)Atypical lipomatous neoplasm/well-differentiated liposarcomaSupernumerary ring chromosomes; giant marker chromosomesAmplification of region 12q13-15, including MDM2, CDK4, HMGA2, SAS, GL1
(3)Dedifferentiated liposarcomaSupernumerary ring chromosomes; giant marker chromosomesAmplification of region 12q14-15, including MDM2, CDK4, HMGA2, SAS, GL1
(4)Pleomorphic liposarcomaComplex alterationsUNKNOWN

(NCCN guidelines V.2.2009).