Nonalcoholic Steatohepatitis in a Patient with Ataxia-Telangiectasia
Figure 1
Histological changes in liver biopsy from patient with ataxia-telangiectasia. Hepatic lobule showing hepatocytes with macrovesicular and multivesicular steatosis (hematoxylin-eosin (a)) and perisinusoidal and pericellular fibrosis around ballooning hepatocytes, some containing Mallory-Denk bodies (arrow) (Gomori trichrome (b)), which are more evident with immunohistochemical staining for p62 protein, arrows (c) (original magnification: ×10, ×20, and ×40, resp.).
