Low-Dose Tolvaptan for the Treatment of Dilutional Hyponatremia in Cirrhosis: A Case Report and Literature Review

Table 1

Serum sodium concentrations and urine volumes of the present patient under the treatment of different doses of tolvaptan.

Data (day)	Baseline*	1	2	3	4	5	8	11	14	17	20	30	60	120	1 (yr)
Dosage of tolvaptan (mg)	NA	15	15	7.5	7.5	5	5	5	5	5	5		NA	NA	NA
Urine volume (mL)	2050	4400	6100	4050	4200	3100	2750	3000	3550	3800	2750	4300	4000	NA	NA
Serum sodium (mmol/L)	132	117	123	130	130	128	NA	128	NA	127	NA	129	135	NA	138
Total bilirubin (μmol/L)	317	244	NA	246	NA	227	NA	196	NA	199	NA	157	92	38	35
ALT (U/L)	52	51	NA	NA	44	NA	NA	34	30	28	NA	33	17	20	17
PT (s)	27.3	23.2	NA	NA	25	NA	NA	24.1	24.9	23.8	NA	21.8	22.4	19.6	14.2
BP (mmHg)	124/69	114/64	NA	NA	NA	NA	107/62	104/72	114/68	NA	122/71	115/65	127/70	NA	125/65
Body weight (Kg)	76	67.5	65	66.5	66.5	69	NA	NA	65.5	NA	61	61.5	NA	NA	71
Child-Pugh score	14	14	NA	NA	NA	NA	NA	NA	NA	NA	NA	11	10	7	5

∗Baseline: the data was from the first day when the patient was admitted.