Case Report
Severe Aplastic Anemia following Parvovirus B19-Associated Acute Hepatitis
Table 1
Initial acute hepatitis workup.
| | Hepatitis A IgM | Nonreactive | | Hepatitis B core IgM | Nonreactive | | Hepatitis B surface antigen | Nonreactive | | HBV-DNA (real-time PCR) | Negative | | Hepatitis C IgG antibody | Nonreactive | | HIV 1 & 2 antibody | Nonreactive | | HTLV 1 & 2 antibody | Nonreactive | | CMV antigenemia (C7-HRP) | Negative | | HSV IgG antibody (EIA) | Positive | | HSV IgM antibody (EIA) | Negative | | VZV IgG antibody (EIA) | Positive | | VZV IgM antibody (EIA) | Negative | | EBV IgG antibody (FA) | Positive | | EBV IgM antibody (FA) | Negative | | EB nuclear antigen (EBNA) IgG (FA) | Positive | | EBV ultraquantitative | Negative | | Echo virus type 3 antibody (FA) | Negative | | Parvovirus B19 IgM antibody (EIA) | Positive | | Parvovirus B19 DNA PCR | Positive | | Antinuclear antibodies | Negative | | Antimitochondrial antibodies | Negative | | TSH (μIU/ml) | 0.48 | | FT3 (pg/ml) | 1.5 | | FT4 (ng/ml) | 1.24 | | PR3-ANCA (U/ml) | Negative | | MPO-ANCA (U/ml) | Negative | | Ferritin (ng/ml) | 1199.5 | | Iron (μg/dl) | 211 | | TIBC (μg/dl) | 227 | | Ceruloplasmin (mg/dl) | 24.4 | | IgG (mg/dl) | 967 | | IgA (mg/dl) | 182.1 | | IgM (mg/dl) | 90.7 | | AFP tumor marker (ng/ml) | 4835.6 | | HGF (ng/ml) | 3.59 |
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