Case Report
Herpes Simplex Virus Hepatitis: A Presentation of Multi-Institutional Cases to Promote Early Diagnosis and Management of the Disease
Table 2
Epidemiology based on two large literature reviews.
| | Norvell et al. | Kaufman et al. | | Number (%) | Number (%) |
| | 137 | 52 | Age (mean, yrs) | 34 | N/A | Gender | | N/A | (i) Male | 51/137 (38) | | (ii) Female | 86/137 (62) | | Immunosuppressed | 72/137 (53) | 35/52 (67) | Pregnant | 32/137 (23) | 9/52 (17) | Fever | 98/100 (98) | 42/52 (82) | Herpetic lesions | 54/123 (44) | 29/52 (57) | Mean peak ALT or AST | 4927 | N/A | Leukopenia | 50/70 (71) | 22/52 (43) | Thrombocytopenia | 59/63 (93) | 23/52 (45) | Coagulopathy | 93/111 (83) | 10/52 (20) | Acute Renal Failure | 34/52 (65) | N/A | Death | | | (i) Acyclovir | 25/49 (51) | 5/9 (55) | (ii) No Acyclovir | 74/84 (88) | 34/43 (80) |
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ALT: alanine aminotransferase; AST: aspartate aminotransferase; N/A: not available.
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