Cervical Spinal Cord Compression: A Rare Presentation of Hepatocellular Carcinoma

Table 1

Spinal cord compression due to HCC–Review of Literature.

Authors	Year	Underlying liver disease	Area of involvement	Presenting symptom	Intervention
Kantharia et al. [11]	1993	Alcoholic and hepatitis C with cirrhosis	T10	Low back pain	Steroids and palliative radiation
Yang et al. [3]	1997	Hepatitis B	Four cases with thoracic spine and one with cervical spine	Two cases with low back pain; One case with hip and pelvic pain; One case with abdominal pain; One case with left upper extremity weakness	Palliative radiotherapy
Garcia and Castillo [12]	2005	Hepatitis B	T9	Low back pain and lower extremity weakness	High dose glucocorticoid and radiation
Doval et al. [13] (case series of 4 cases)	2006	Hepatitis B	Thoracic in 3 cases and thoracic and lumbar in 1 case	Low back pain	Chemotherapy
Nakamura et al. [9]	2006	Hepatitis B and hepatitis C	Cervical in 4 cases; thoracic spine in 15; lumbar spine in 5 cases	Neck pain and back pain	Radiotherapy
Vargas et al. [14]	2011	Hepatitis B	T4 and L5	Low back pain	Surgical decompression
Sherif et al. [15]	2012	Alcoholic cirrhosis	T12	Paraplegia	Surgical decompression
Zhang et al. [4] (case series)	2013	Hepatitis B in all cases	Five cases in cervical spine; Nineteen in thoracic spine; Twelve in lumbar spine	Pain and neurological symptoms	18 patients, preoperative embolization; All patients, surgical decompression
Nangolo et al. [16]	2014	Chronic hepatitis B and alcohol use	L1	Lower extremity weakness	Comfort care
Vallianou et al. [6]	2014	Chronic hepatitis B	C6, C7	Upper extremity muscle pain and paresthesia	Chemotherapy and radiotherapy
Hwang et al. [5]	2015	Hepatitis B	C5 and pelvis	Upper extremity weakness and tingling	Steroid and surgery; TACE; Sorafenib