Case Report

Hepatic Iron Overload following Liver Transplantation from a C282Y/H63D Compound Heterozygous Donor

Table 1


Reference #Year of publicationDonorRecipientReason for transplantTime from OLT to HH development
(months)
Outcome

[5]1999C282Y
homozygote
liver & intestine
Non-HHCholestatic liver disease &
short bowel syndrome
21Biochemical abnormalities consistent with HH

[6]2003C282Y heterozygote livernew missense mutation
R6S
Alcoholic cirrhosis49Treated with phlebotomy

[7]2009C282Y homozygote liverH63D heterozygoteHBV+HCV +ethanol60Died due to lung cancer

[4]2011C282Y homozygote liverNon-HHFulminant HBV reactivation24Treated with phlebotomy

Present
case
2016C282Y/H63D
compound heterozygote
Non-HHPSC and Crohn’s disease18Planned for phlebotomy