Case Report

Rupture of Hepatocellular Carcinoma after Transarterial Chemoembolization followed by Massive Gastric Bleeding

Table 1

Previously reported cases of HCC rupture after TACE.

No.AuthorYearCountryAgeGenderEtiologyCirrhosisTumor size (cm)LocationIntervalTreatmentOutcomeCause of death,

1Tu [2], Jia [6]2016, 2013China45MHBVPresent9Right10ConservativeDiedN.A
261MN.A.Absent13Right6TAEAlive
353MHBVPresent11Right+Left7ConservativeDiedN.A.
457MHBVAbsent14Right+Left9TAEAlive
564MN.A.Absent16Right+Left17ConservativeAlive
667F/MN.A.Absent16Right+Left13ConservativeAlive
7Singh Bhinder [7]2015USA67Malcohol, HCVPresent4VII1TAEAlive
8Park [8]2011Korea52MHBV, alcoholPresent12.3VII30ConservativeDiedHepatic failure, more than 1 year after TACE
9Bruls [9]2011Belgium78MalcoholPresent7II, IV3 weeksConservativeDiedTumor rupture, 2 month after TACE
10Ritter [10]2011Germany74MalcoholPresent16III, IVb14 hoursConservativeDiedFew hours after tumor rupture
11Sun [11]2010China28FN.A.N.A.13Right1 monthTAEAlive
1242FN.A.N.A.11Right3TAEAlive
1383FN.A.N.A.14Right5 monthTAEDiedRespiratory failure, 1 week after rupture
1451MN.A.N.A.7Right16 hoursTAEAlive
1547MN.A.N.A.10Right7 monthsTAEAlive
16Nawawi [12]2010Malaysia66MalcoholPresent3.5N.A.N.A.N.A.DiedTumor rupture, 2 month after TACE
17Reso [13]2009Canada90MN.A.N.A.11Right4 hoursConservativeDiedRespiratory failure, 16 days after TACE
18Reichman [14]2009USA53MHBVPresent6VII, VIII6 hoursLaparotomyDiedShortly after tumor rupture
19Battula [15]2007UK61MN.A.Present11Right2LaparotomyDiedTumor rupture, 2 days after TACE
2069MN.A.Present13Right24ConservativeAlive
21Yeh [16]2002Taiwan45MHCVPresentN.A.IV-VIII2 monthLaparotomyDiedHepatic failure, one month after surgery

HBV: hepatitis B virus: HCC: hepatocellular carcinoma: HCV: hepatitis C virus: TAE: transarterial embolization: TACE: transarterial chemoembolization: USA: the United States of America: UK: United Kingdom.