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Author (year) [ref.] | Number Of cases | Age | Sex | Duration of GC containing supplement use | Presenting symptoms | Pattern of liver injury | Updated RUCAM score | Number of cases that underwent liver transplant | Mortality |
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Stevens et al. [10] (2005) | 2 | 28.5 | M | 5 weeks; 5 days | Fatigue, jaundice | Hepatocellular; cholestatic | 8 | 0 | 0 |
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Jones and Andrews [11] (2007) | 1 | 19 | M | 120 days | Nausea, vomiting, and jaundice | Hepatocellular | 7 | 0 | 0 |
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Laczek and Duncan [12] (2008) | 3 | 24.33 | M | 60-90 days | Malaise, jaundice, and pruritus | 2 hepatocellular; 1 cholestatic | 8 | 0 | 0 |
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Dara et al. [13] (2008) | 2 | 36.5 | F | 7 days; 14 days | Nausea, vomiting, fatigue, anorexia, and abdominal pain | Hepatocellular | 8 | 0 | 0 |
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Shim and Saab [14] (2009) | 1 | 28 | M | 90 days | Fatigue, jaundice | Hepatocellular | 8 | 0 | 0 |
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Fong et al. [15] (2010) | 8 | 30.9 | 6M; 2 F | 7 to 56 days | Nausea, vomiting, fatigue, and itching abdominal pain | Hepatocellular | 7-8āā NA for 3 patients needing transplant | 3 | 0 |
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Danan and Teschke [9] (2010) | 1 | 19 | M | 7 days | Fever, fatigue, myalgia, arthralgia, and rash | Cholestatic | 7 | 0 | 0 |
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Sharma et al. [16] (2014) | 1 | 27 | M | Unknown | Nausea, vomiting, abdominal pain, and jaundice | Hepatocellular | 7 | 0 | 0 |
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Lee et al. [17] (2014) | 1 | 39 | F | 2 days | Abdominal pain, anorexia, nausea, dyspepsia, fatigue, and jaundice | Hepatocellular | 8 | 0 | 0 |
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Melendez-Rosado et al. [7] (2015) | 1 | 42 | F | 7 days | Nausea, abdominal pain | Hepatocellular | 7 | 0 | 0 |
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Corey et al. [2] (2016) | 1 | 52 | F | 25 days | Jaundice, decreased appetite, fatigue, and confusion | Hepatocellular | NA | 1 | 0 |
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Smith et al. [18] (2016) | 1 | 26 | M | 7 days | Jaundice, fatigue | Hepatocellular | NA | 1 | 0 |
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Lunsford et al. [19] (2016) | 1 | 34 | M | 150 days | Nausea, vomiting, abdominal pain, and dark urine | Hepatocellular | NA | 1 | 0 |
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Kothadia et al. (present case) | 1 | 26 | F | 28 days | Fever, nausea, vomiting, abdominal pain, malaise, fatigue, and jaundice | Hepatocellular | 8 | 0 | 0 |
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